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Chemotherapy Infusion Cost in Missouri (2026): Average Prices & What You'll Pay

What does a chemotherapy infusion cost in Missouri?

Where you have a chemotherapy infusion done in Missouri swings the bill from $280 to $639 for identical care. The median cash price across 77 reporting hospitals is $398. The numbers are pulled directly from federally mandated hospital price transparency files. The sections below break this down by coverage and by insurer.

Three low-priced facilities in Missouri, from hospital price files

  • New Liberty Hospital Corporation · Liberty, MO $135
  • Ssm Health St. Joseph Hospital-St Charles · Saint Charles, MO $136
  • SSM Health Care St. Louis · Wentzville, MO $136

All 77 facilities are listed below, free.

Where chemotherapy infusion costs vary in Missouri

Pins show hospitals with price-transparency data (colored by vs. state average) and nearby outpatient clinics and other facilities (colored by type). Click any pin for facility name and estimated cost range.

Hospital (below avg) Hospital (above avg) Click a pin for details.

26+ people checked prices near them this month.

What you pay for a chemotherapy infusion depends on where you go and what is billed separately. Most patients find out after.

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  • ✓ The drugs are not included: Chemotherapy drugs are billed on their own and are usually most of the bill.
  • ✓ Time: The first hour is priced here, and each additional hour is an add-on.
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Cheapest Chemotherapy Infusion Providers in Missouri

Based on declared cash/self-pay prices from CMS hospital price transparency files.

# Facility City Price vs median ($398)
1 New Liberty Hospital Corporation Liberty, MO $135 $263 below
2 Ssm Health St. Joseph Hospital-St Charles Saint Charles, MO $136 $262 below
3 SSM Health Care St. Louis Wentzville, MO $136 $262 below
4 Carroll County Memorial Hospital Carrollton, MO $149 $249 below
5 Ssm Health Saint Louis University Hospital Saint Louis, MO $157 $241 below
6 SKAGGS COMMUNITY HOSPITAL ASSOCIATION Branson, MO $181 $217 below
7 LESTER E COX MEDICAL CENTERS Springfield, MO $201 $197 below
8 SSM Regional Health Services Jefferson City, MO $234 $164 below

Prices are declared self-pay rates. Contact each facility for a formal quote before scheduling.

Before you book: three questions that change the price

  1. Is this the self-pay price, and does it include the doctor, anesthesia and any lab or pathology? Those are often billed separately.
  2. Can you give me the price in writing, with the billing codes it covers?
  3. What happens to the price if something extra is needed during the procedure?

Estimate your out-of-pocket cost →  ·  When the bills arrive, we check them for errors →

Quick take

  • New Liberty Hospital Corporation is the lowest-cost option at $135 - $263 below the median posted price ($398), just by choosing where you go.
  • Ask for the cash price if your deductible isn't met - the median cash price here is $374, and it's often lower than what insurance pays before your deductible is satisfied.
  • Doctor offices and independent clinics may charge differently from hospitals for the same service and may not appear in this hospital-only dataset. Ask your doctor whether another site is an option.
Chemotherapy infusion prices by coverage in Missouri, October 2026
CoverageHospitals with a rateTypical rangeMedian
Medicare (national rate)—$337 to $337$337
With insurance (commercial, average)62$277 to $827$450
Without insurance (cash price)82$133 to $828$374
Anthem Blue Cross and Blue Shield47$192 to $963$543
UnitedHealthcare40$311 to $1,030$535
Cigna35$356 to $1,178$624
Aetna33$243 to $1,042$524

Rates are negotiated allowed amounts and cash prices from hospital price-transparency files (October 2026), shown at each hospital’s lowest-priced typical billing code for this procedure. Facility fees only. The typical range is the middle 80% of hospitals, not a quote for your visit.

How much does a chemotherapy infusion cost with Medicare in Missouri?

Medicare's national hospital outpatient payment for chemotherapy infusion is about $337 to $337 (typically near $337). After the $257 Part B deductible, you generally pay 20% of the Medicare-approved amount, about $67 on a $337 payment, with no out-of-pocket cap unless you have supplemental coverage or a Medicare Advantage plan.

Doctor, anesthesia and pathology fees are billed separately. Medicare rates are national CMS amounts, adjusted slightly by local wage levels.

How much does a chemotherapy infusion cost with insurance in Missouri?

Across 62 Missouri hospitals, the negotiated rates commercial insurers pay for chemotherapy infusion average $277 to $827 per hospital, with a median near $450. That is the amount your plan and you pay the hospital together; you owe your deductible, then coinsurance, up to your out-of-pocket maximum.

Each hospital’s figure is the average of the commercial insurers it lists. Medicare, Medicare Advantage and Medicaid rates are excluded.

How much does a chemotherapy infusion cost without insurance in Missouri?

Cash (self-pay) prices for chemotherapy infusion at 82 Missouri hospitals range from $133 to $828, with a median of $374. Ask for the cash or self-pay price and for any financial-assistance discount before you book; both can be lower than the posted price.

Cash prices are the hospital’s published discounted rate for patients paying without insurance.

How much does a chemotherapy infusion cost with Anthem Blue Cross and Blue Shield in Missouri?

Anthem Blue Cross and Blue Shield negotiated rates for chemotherapy infusion at 47 Missouri hospitals range from $192 to $963, with a median near $543. Your own cost depends on your plan’s deductible and coinsurance, and on whether the hospital is in your network.

Includes Blue Cross and Blue Shield and Anthem plans listed by each hospital.

How much does a chemotherapy infusion cost with UnitedHealthcare in Missouri?

UnitedHealthcare negotiated rates for chemotherapy infusion at 40 Missouri hospitals range from $311 to $1,030, with a median near $535. If a hospital is out of network for your UnitedHealthcare plan, you may owe more than the negotiated rate, so check the network first.

How much does a chemotherapy infusion cost with Cigna in Missouri?

Cigna negotiated rates for chemotherapy infusion at 35 Missouri hospitals range from $356 to $1,178, with a median near $624. If a hospital is out of network for your Cigna plan, you may owe more than the negotiated rate, so check the network first.

How much does a chemotherapy infusion cost with Aetna in Missouri?

Aetna negotiated rates for chemotherapy infusion at 33 Missouri hospitals range from $243 to $1,042, with a median near $524. If a hospital is out of network for your Aetna plan, you may owe more than the negotiated rate, so check the network first.

How where you go changes what you pay for chemotherapy infusion

The same chemotherapy infusion bundles different services depending on the setting - facility fee, surgeon fee, and anesthesia each arrive as separate bills. Estimated ranges below reflect the typical full bundled cost, including all expected charges.

Hospital Outpatient
$287–$4,267
  • Facility fee $102–$3,775
  • Professional fee $185–$492

Estimated from CMS fee schedules + commercial rate multipliers

Hospital Inpatient
$334–$2,035
  • Facility fee $149–$1,543
  • Professional fee $185–$492

Estimated from CMS fee schedules + commercial rate multipliers

BJC HealthCare, SSM Health, Mercy Health, and CoxHealth divide Missouri roughly by region, with meaningful inter-system competition in both St. Louis and Kansas City. Barnes-Jewish Hospital (BJC) is the dominant academic medical center. Rural Missouri - particularly the Ozarks - has significant critical access hospital coverage where pricing structures differ from PPS hospitals.

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Why prices vary - and what it means for your coverage

A small number of hospitals (4) report prices above $1,506, including St Louis Childrens Hospital at $1,543, which drives most of the overall spread - excluding them, most facilities cluster in a much tighter band. Setting matters too: the median outpatient price is $353 versus $711 inpatient (about 2× more), so where a procedure happens often matters more than which hospital you pick.

What you pay out of pocket on top of this depends on your deductible, your plan's out-of-pocket maximum, and whether every provider involved is in-network - not just the facility.

Your situation Estimated out-of-pocket
Deductible not yet met ~$398
Deductible met - 20% coinsurance ~$80
Out-of-network provider $876+

Frequently asked questions: chemotherapy infusion costs in Missouri

How much does a chemotherapy infusion cost in Missouri?

The typical insurer-negotiated rate is $136, with most facilities between $113 and $286 (based on 77 hospitals reporting negotiated rates). Posted cash prices at the middle 80% of Missouri hospitals run $133–$828; outlier facilities above and below that range are left out. What you pay depends on the facility, your insurance, and whether you have met your deductible.

Where is the cheapest place to get a chemotherapy infusion in Missouri?

Based on declared prices, the lowest posted price in our Missouri data is New Liberty Hospital Corporation in Liberty at about $135. By metro, Kansas City has the lowest median ($108).

Why is a chemotherapy infusion so much cheaper at some Missouri hospitals?

Typical prices vary about 2.5× (25th to 70th percentile of negotiated rates) because each hospital sets its own list price, cash discount, and insurer-negotiated rates. In Missouri, the median cash (self-pay) price is $374 versus a median negotiated rate of $450 - cash is the lower number at many hospitals. Asking for the cash price as well as your insurer's negotiated rate is often the single biggest lever on what you pay.

How much will I actually pay out of pocket for a chemotherapy infusion in Missouri?

Your out-of-pocket cost depends on your deductible, coinsurance, out-of-pocket maximum, and whether the facility is in-network - not just the sticker price. If you have not met your deductible, you will typically pay the negotiated rate in full until you do. Use the CostKits cost forecaster to estimate your specific out-of-pocket amount before you go.

Before you book

Other procedures in Missouri

Chemotherapy Infusion, elsewhere


CostKits compiles hospital price transparency data to help families make informed decisions. Track and manage your healthcare costs (free account).

Other Procedure Costs in Missouri

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Emergency care

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About the Author

John Caruso, FSA, MAAA

Healthcare actuary with 20+ years of experience in insurance pricing, medical billing systems, and healthcare cost analytics.

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Published October 29, 2026 · Updated October 29, 2026

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