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Chemotherapy Infusion Cost in Florida (2026): Average Prices & What You'll Pay

What does a chemotherapy infusion cost in Florida?

You could pay $168 or $541 for the same chemotherapy infusion in Florida - depending entirely on which facility you choose. The median cash price across 129 reporting hospitals is $327. This data comes directly from hospital price transparency files published under federal law. The sections below break this down by coverage and by insurer.

Three low-priced facilities in Florida, from hospital price files

  • HCA FLORIDA PUTNAM HOSPITAL · Palatka, FL $143
  • HCA FLORIDA LAKE CITY HOSPITAL · Live Oak, FL $143
  • HCA FLORIDA OCALA HOSPITAL · Wildwood, FL $143

All 129 facilities are listed below, free.

Where chemotherapy infusion costs vary in Florida

Pins show hospitals with price-transparency data (colored by vs. state average) and nearby outpatient clinics and other facilities (colored by type). Click any pin for facility name and estimated cost range.

Hospital (below avg) Hospital (above avg) Click a pin for details.

26+ people checked prices near them this month.

What you pay for a chemotherapy infusion depends on where you go and what is billed separately. Most patients find out after.

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  • ✓ The drugs are not included: Chemotherapy drugs are billed on their own and are usually most of the bill.
  • ✓ Time: The first hour is priced here, and each additional hour is an add-on.
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Cheapest Chemotherapy Infusion Providers in Florida

Based on declared cash/self-pay prices from CMS hospital price transparency files.

# Facility City Price vs median ($327)
1 HCA FLORIDA PUTNAM HOSPITAL Palatka, FL $143 $184 below
2 HCA FLORIDA LAKE CITY HOSPITAL Live Oak, FL $143 $184 below
3 HCA FLORIDA OCALA HOSPITAL Wildwood, FL $143 $184 below
4 HCA FLORIDA WEST MARION HOSPITAL Ocala, FL $143 $184 below
5 HCA FLORIDA WEST HOSPITAL Pensacola, FL $143 $184 below
6 HCA FLORIDA OSCEOLA HOSPITAL St. Cloud, FL $143 $184 below
7 UCF LAKE NONA HOSPITAL Orlando, FL $143 $184 below
8 HCA FLORIDA OAK HILL HOSPITAL Spring Hill, FL $143 $184 below

Prices are declared self-pay rates. Contact each facility for a formal quote before scheduling.

Before you book: three questions that change the price

  1. Is this the self-pay price, and does it include the doctor, anesthesia and any lab or pathology? Those are often billed separately.
  2. Can you give me the price in writing, with the billing codes it covers?
  3. What happens to the price if something extra is needed during the procedure?

Estimate your out-of-pocket cost →  ·  When the bills arrive, we check them for errors →

Quick take

  • HCA FLORIDA PUTNAM HOSPITAL is the lowest-cost option at $143 - $184 below the median posted price ($327), just by choosing where you go.
  • Ask for the cash price if your deductible isn't met - the median cash price here is $327, and it's often lower than what insurance pays before your deductible is satisfied.
  • Doctor offices and independent clinics may charge differently from hospitals for the same service and may not appear in this hospital-only dataset. Ask your doctor whether another site is an option.
Chemotherapy infusion prices by coverage in Florida, October 2026
CoverageHospitals with a rateTypical rangeMedian
Medicare (national rate)—$337 to $337$337
With insurance (commercial, average)71$207 to $754$408
Without insurance (cash price)135$143 to $1,011$327
Florida Blue8$244 to $1,090$749
Aetna48$122 to $666$246
Cigna30$67 to $1,005$258
Humana23$108 to $464$346

Rates are negotiated allowed amounts and cash prices from hospital price-transparency files (October 2026), shown at each hospital’s lowest-priced typical billing code for this procedure. Facility fees only. The typical range is the middle 80% of hospitals, not a quote for your visit.

How much does a chemotherapy infusion cost with Medicare in Florida?

Medicare's national hospital outpatient payment for chemotherapy infusion is about $337 to $337 (typically near $337). After the $257 Part B deductible, you generally pay 20% of the Medicare-approved amount, about $67 on a $337 payment, with no out-of-pocket cap unless you have supplemental coverage or a Medicare Advantage plan.

Doctor, anesthesia and pathology fees are billed separately. Medicare rates are national CMS amounts, adjusted slightly by local wage levels.

How much does a chemotherapy infusion cost with insurance in Florida?

Across 71 Florida hospitals, the negotiated rates commercial insurers pay for chemotherapy infusion average $207 to $754 per hospital, with a median near $408. That is the amount your plan and you pay the hospital together; you owe your deductible, then coinsurance, up to your out-of-pocket maximum.

Each hospital’s figure is the average of the commercial insurers it lists. Medicare, Medicare Advantage and Medicaid rates are excluded.

How much does a chemotherapy infusion cost without insurance in Florida?

Cash (self-pay) prices for chemotherapy infusion at 135 Florida hospitals range from $143 to $1,011, with a median of $327. Ask for the cash or self-pay price and for any financial-assistance discount before you book; both can be lower than the posted price.

Cash prices are the hospital’s published discounted rate for patients paying without insurance.

How much does a chemotherapy infusion cost with Florida Blue?

Florida Blue negotiated rates for chemotherapy infusion at 8 Florida hospitals range from $244 to $1,090, with a median near $749. Your own cost depends on your plan’s deductible and coinsurance, and on whether the hospital is in your network.

Includes Blue Cross and Blue Shield and Anthem plans listed by each hospital.

How much does a chemotherapy infusion cost with Aetna in Florida?

Aetna negotiated rates for chemotherapy infusion at 48 Florida hospitals range from $122 to $666, with a median near $246. If a hospital is out of network for your Aetna plan, you may owe more than the negotiated rate, so check the network first.

How much does a chemotherapy infusion cost with Cigna in Florida?

Cigna negotiated rates for chemotherapy infusion at 30 Florida hospitals range from $67 to $1,005, with a median near $258. If a hospital is out of network for your Cigna plan, you may owe more than the negotiated rate, so check the network first.

How much does a chemotherapy infusion cost with Humana in Florida?

Humana negotiated rates for chemotherapy infusion at 23 Florida hospitals range from $108 to $464, with a median near $346. If a hospital is out of network for your Humana plan, you may owe more than the negotiated rate, so check the network first.

How where you go changes what you pay for chemotherapy infusion

The same chemotherapy infusion bundles different services depending on the setting - facility fee, surgeon fee, and anesthesia each arrive as separate bills. Estimated ranges below reflect the typical full bundled cost, including all expected charges.

Hospital Outpatient
$213–$4,162
  • Facility fee $28–$3,670
  • Professional fee $185–$492

Estimated from CMS fee schedules + commercial rate multipliers

Hospital Inpatient
$364–$2,211
  • Facility fee $179–$1,719
  • Professional fee $185–$492

Estimated from CMS fee schedules + commercial rate multipliers

Florida has one of the most fragmented hospital markets in the country - HCA Healthcare (the nation's largest for-profit system, headquartered in Nashville), AdventHealth, BayCare, and dozens of independents compete aggressively in major metros. South Florida prices track higher than the rest of the state, driven by higher wage indices and a larger share of complex specialty care. Rural northern Florida has extensive critical access hospital coverage.

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Why prices vary - and what it means for your coverage

A small number of hospitals (4) report prices above $1,540, including NICKLAUS CHILDREN'S HOSPITAL at $1,812, which drives most of the overall spread - excluding them, most facilities cluster in a much tighter band. Setting matters too: the median outpatient price is $313 versus $848 inpatient (about 2.7× more), so where a procedure happens often matters more than which hospital you pick.

None of the prices above are what you'll necessarily owe: your deductible, out-of-pocket maximum, and each provider's network status all still apply.

Your situation Estimated out-of-pocket
Deductible not yet met ~$327
Deductible met - 20% coinsurance ~$65
Out-of-network provider $719+

Frequently asked questions: chemotherapy infusion costs in Florida

How much does a chemotherapy infusion cost in Florida?

The typical insurer-negotiated rate is $152, with most facilities between $142 and $275 (based on 125 hospitals reporting negotiated rates). Posted cash prices at the middle 80% of Florida hospitals run $143–$1,011; outlier facilities above and below that range are left out. What you pay depends on the facility, your insurance, and whether you have met your deductible.

Where is the cheapest place to get a chemotherapy infusion in Florida?

Based on declared prices, the lowest posted price in our Florida data is HCA FLORIDA PUTNAM HOSPITAL in Palatka at about $143. By metro, Tampa has the lowest median ($244).

Why is a chemotherapy infusion so much cheaper at some Florida hospitals?

Typical prices vary about 1.9× (25th to 70th percentile of negotiated rates) because each hospital sets its own list price, cash discount, and insurer-negotiated rates. In Florida, the median cash (self-pay) price is $327 versus a median negotiated rate of $408 - cash is the lower number at many hospitals. Asking for the cash price as well as your insurer's negotiated rate is often the single biggest lever on what you pay.

How much will I actually pay out of pocket for a chemotherapy infusion in Florida?

Your out-of-pocket cost depends on your deductible, coinsurance, out-of-pocket maximum, and whether the facility is in-network - not just the sticker price. If you have not met your deductible, you will typically pay the negotiated rate in full until you do. Use the CostKits cost forecaster to estimate your specific out-of-pocket amount before you go.

Before you book

Other procedures in Florida

Chemotherapy Infusion, elsewhere


CostKits compiles hospital price transparency data to help families make informed decisions. Track and manage your healthcare costs (free account).

Other Procedure Costs in Florida

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About the Author

John Caruso, FSA, MAAA

Healthcare actuary with 20+ years of experience in insurance pricing, medical billing systems, and healthcare cost analytics.

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Published October 29, 2026 · Updated October 29, 2026

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