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Chemotherapy Infusion Cost in Minnesota (2026): Average Prices & What You'll Pay

What does a chemotherapy infusion cost in Minnesota?

The same chemotherapy infusion in Minnesota might cost you $225 at one facility and $470 at another - the building you walk into drives the difference. The median cash price across 93 reporting hospitals is $331. These figures come straight from hospital price transparency files published under federal law. The sections below break this down by coverage and by insurer.

Once you have a bill or an appointment on the calendar, CostKits can help you keep it all organized.

Where chemotherapy infusion costs vary in Minnesota

Pins show hospitals with price-transparency data (colored by vs. state average) and nearby outpatient clinics and other facilities (colored by type). Click any pin for facility name and estimated cost range.

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26+ people checked prices near them this month.

What you pay for a chemotherapy infusion depends on where you go and what is billed separately. Most patients find out after.

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  • ✓ The drugs are not included: Chemotherapy drugs are billed on their own and are usually most of the bill.
  • ✓ Time: The first hour is priced here, and each additional hour is an add-on.
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Cheapest Chemotherapy Infusion Providers in Minnesota

Based on declared cash/self-pay prices from CMS hospital price transparency files.

# Facility City Price vs median ($331)
1 Aspirus Lake View Hospital Two Harbors, MN $148 $183 below
2 Allina Health Systems MN $148 $183 below
3 Regions Hospital St. Paul, MN $151 $180 below
4 Mayo Clinic Health System Albert Lea, MN $161 $170 below
5 Mayo Clinic Rochester, MN $162 $169 below
6 Alomere Health Alexandria, MN $174 $157 below
7 County of Murray Slayton, MN $178 $153 below
8 Aspirus St. Luke’s Hospital Duluth, MN $183 $148 below

Prices are declared self-pay rates. Contact each facility for a formal quote before scheduling.

Before you book: three questions that change the price

  1. Is this the self-pay price, and does it include the doctor, anesthesia and any lab or pathology? Those are often billed separately.
  2. Can you give me the price in writing, with the billing codes it covers?
  3. What happens to the price if something extra is needed during the procedure?

Estimate your out-of-pocket cost →  ·  When the bills arrive, we check them for errors →

Quick take

  • Aspirus Lake View Hospital is the lowest-cost option at $148 - $183 below the median posted price ($331), just by choosing where you go.
  • Ask for the cash price if your deductible isn't met - the median cash price here is $331, and it's often lower than what insurance pays before your deductible is satisfied.
  • Doctor offices and independent clinics may charge differently from hospitals for the same service and may not appear in this hospital-only dataset. Ask your doctor whether another site is an option.
Chemotherapy infusion prices by coverage in Minnesota, October 2026
CoverageHospitals with a rateTypical rangeMedian
Medicare (national rate)—$337 to $337$337
With insurance (commercial, average)82$314 to $773$504
Without insurance (cash price)109$146 to $660$331
Blue Cross and Blue Shield of Minnesota73$211 to $737$375
UnitedHealthcare71$349 to $897$541
Cigna47$335 to $912$555
Aetna41$354 to $872$660

Rates are negotiated allowed amounts and cash prices from hospital price-transparency files (October 2026), shown at each hospital’s lowest-priced typical billing code for this procedure. Facility fees only. The typical range is the middle 80% of hospitals, not a quote for your visit.

How much does a chemotherapy infusion cost with Medicare in Minnesota?

Medicare's national hospital outpatient payment for chemotherapy infusion is about $337 to $337 (typically near $337). After the $257 Part B deductible, you generally pay 20% of the Medicare-approved amount, about $67 on a $337 payment, with no out-of-pocket cap unless you have supplemental coverage or a Medicare Advantage plan.

Doctor, anesthesia and pathology fees are billed separately. Medicare rates are national CMS amounts, adjusted slightly by local wage levels.

How much does a chemotherapy infusion cost with insurance in Minnesota?

Across 82 Minnesota hospitals, the negotiated rates commercial insurers pay for chemotherapy infusion average $314 to $773 per hospital, with a median near $504. That is the amount your plan and you pay the hospital together; you owe your deductible, then coinsurance, up to your out-of-pocket maximum.

Each hospital’s figure is the average of the commercial insurers it lists. Medicare, Medicare Advantage and Medicaid rates are excluded.

How much does a chemotherapy infusion cost without insurance in Minnesota?

Cash (self-pay) prices for chemotherapy infusion at 109 Minnesota hospitals range from $146 to $660, with a median of $331. Ask for the cash or self-pay price and for any financial-assistance discount before you book; both can be lower than the posted price.

Cash prices are the hospital’s published discounted rate for patients paying without insurance.

How much does a chemotherapy infusion cost with Blue Cross and Blue Shield of Minnesota?

Blue Cross and Blue Shield of Minnesota negotiated rates for chemotherapy infusion at 73 Minnesota hospitals range from $211 to $737, with a median near $375. Your own cost depends on your plan’s deductible and coinsurance, and on whether the hospital is in your network.

Includes Blue Cross and Blue Shield and Anthem plans listed by each hospital.

How much does a chemotherapy infusion cost with UnitedHealthcare in Minnesota?

UnitedHealthcare negotiated rates for chemotherapy infusion at 71 Minnesota hospitals range from $349 to $897, with a median near $541. If a hospital is out of network for your UnitedHealthcare plan, you may owe more than the negotiated rate, so check the network first.

How much does a chemotherapy infusion cost with Cigna in Minnesota?

Cigna negotiated rates for chemotherapy infusion at 47 Minnesota hospitals range from $335 to $912, with a median near $555. If a hospital is out of network for your Cigna plan, you may owe more than the negotiated rate, so check the network first.

How much does a chemotherapy infusion cost with Aetna in Minnesota?

Aetna negotiated rates for chemotherapy infusion at 41 Minnesota hospitals range from $354 to $872, with a median near $660. If a hospital is out of network for your Aetna plan, you may owe more than the negotiated rate, so check the network first.

How where you go changes what you pay for chemotherapy infusion

The same chemotherapy infusion bundles different services depending on the setting - facility fee, surgeon fee, and anesthesia each arrive as separate bills. Estimated ranges below reflect the typical full bundled cost, including all expected charges.

Hospital Outpatient
$293–$1,408
  • Facility fee $108–$916
  • Professional fee $185–$492

Estimated from CMS fee schedules + commercial rate multipliers

Hospital Inpatient
$333–$1,133
  • Facility fee $148–$641
  • Professional fee $185–$492

Estimated from CMS fee schedules + commercial rate multipliers

Mayo Clinic anchors Rochester and draws referral patients from across the Upper Midwest, with pricing that reflects its tertiary-care market position. Allina Health and M Health Fairview (University of Minnesota) compete in the Twin Cities. Minnesota has a reputation for efficient care delivery, but that efficiency doesn't necessarily translate to lower commercial prices in a concentrated market.

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Why prices vary - and what it means for your coverage

Setting matters too: the median outpatient price is $334 versus $308 inpatient, so where a procedure happens often matters more than which hospital you pick.

None of the prices above are what you'll necessarily owe: your deductible, out-of-pocket maximum, and each provider's network status all still apply.

Your situation Estimated out-of-pocket
Deductible not yet met ~$331
Deductible met - 20% coinsurance ~$66
Out-of-network provider $728+

Frequently asked questions: chemotherapy infusion costs in Minnesota

How much does a chemotherapy infusion cost in Minnesota?

The typical insurer-negotiated rate is $225, with most facilities between $110 and $260 (based on 93 hospitals reporting negotiated rates). Posted cash prices at the middle 80% of Minnesota hospitals run $146–$660; outlier facilities above and below that range are left out. What you pay depends on the facility, your insurance, and whether you have met your deductible.

Where is the cheapest place to get a chemotherapy infusion in Minnesota?

Based on declared prices, the lowest posted price in our Minnesota data is Aspirus Lake View Hospital in Two Harbors at about $148. By metro, St. Paul has the lowest median ($295).

Why is a chemotherapy infusion so much cheaper at some Minnesota hospitals?

Typical prices vary about 2.4× (25th to 70th percentile of negotiated rates) because each hospital sets its own list price, cash discount, and insurer-negotiated rates. In Minnesota, the median cash (self-pay) price is $331 versus a median negotiated rate of $504 - cash is the lower number at many hospitals. Asking for the cash price as well as your insurer's negotiated rate is often the single biggest lever on what you pay.

How much will I actually pay out of pocket for a chemotherapy infusion in Minnesota?

Your out-of-pocket cost depends on your deductible, coinsurance, out-of-pocket maximum, and whether the facility is in-network - not just the sticker price. If you have not met your deductible, you will typically pay the negotiated rate in full until you do. Use the CostKits cost forecaster to estimate your specific out-of-pocket amount before you go.

Before you book

Other procedures in Minnesota

Chemotherapy Infusion, elsewhere


CostKits compiles hospital price transparency data to help families make informed decisions. Track and manage your healthcare costs (free account).

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About the Author

John Caruso, FSA, MAAA

Healthcare actuary with 20+ years of experience in insurance pricing, medical billing systems, and healthcare cost analytics.

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Published October 29, 2026 · Updated October 29, 2026

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