Chemotherapy Infusion Cost in South Dakota (2026): Average Prices & What You'll Pay
What does a chemotherapy infusion cost in South Dakota?
The same chemotherapy infusion in South Dakota might cost you $703 at one facility and $883 at another - the building you walk into drives the difference. The median cash price across 37 reporting hospitals is $798. These figures come straight from hospital price transparency files published under federal law. The sections below break this down by coverage and by insurer.
Once you have a bill or an appointment on the calendar, CostKits can help you keep it all organized.
Where chemotherapy infusion costs vary in South Dakota
Pins show hospitals with price-transparency data (colored by vs. state average) and nearby outpatient clinics and other facilities (colored by type). Click any pin for facility name and estimated cost range.
26+ people checked prices near them this month.
What you pay for a chemotherapy infusion depends on where you go and what is billed separately. Most patients find out after.
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Cheapest Chemotherapy Infusion Providers in South Dakota
Based on declared cash/self-pay prices from CMS hospital price transparency files.
| # | Facility | City | Price | vs median ($798) |
|---|---|---|---|---|
| 1 | Avera Sacred Heart Hospital | Yankton, SD | $629 | $169 below |
| 2 | Avera Gregory Hospital | Gregory, SD | $629 | $169 below |
| 3 | Avera Weskota Memorial Med Ctr | Wessington Springs, SD | $642 | $156 below |
| 4 | Winner Regional Healthcare Center | Winner, SD | $672 | $126 below |
| 5 | Sanford Canton Inwood Medical Center | Canton, SD | $673 | $125 below |
| 6 | Platte Healthcare | Platte, SD | $682 | $116 below |
| 7 | Sanford Vermillion Hospital | Vermillion, SD | $695 | $103 below |
| 8 | Prairie Lakes Health Care System Inc. | SD | $705 | $93 below |
Prices are declared self-pay rates. Contact each facility for a formal quote before scheduling.
Before you book: three questions that change the price
- Is this the self-pay price, and does it include the doctor, anesthesia and any lab or pathology? Those are often billed separately.
- Can you give me the price in writing, with the billing codes it covers?
- What happens to the price if something extra is needed during the procedure?
Estimate your out-of-pocket cost → · When the bills arrive, we check them for errors →
Quick take
- Avera Sacred Heart Hospital is the lowest-cost option at $629 - $169 below the median posted price ($798), just by choosing where you go.
- Ask for the cash price if your deductible isn't met - the median cash price here is $798, and it's often lower than what insurance pays before your deductible is satisfied.
- Doctor offices and independent clinics may charge differently from hospitals for the same service and may not appear in this hospital-only dataset. Ask your doctor whether another site is an option.
| Coverage | Hospitals with a rate | Typical range | Median |
|---|---|---|---|
| Medicare (national rate) | — | $337 to $337 | $337 |
| With insurance (commercial, average) | 34 | $351 to $907 | $620 |
| Without insurance (cash price) | 37 | $585 to $1,014 | $798 |
| Wellmark Blue Cross and Blue Shield of South Dakota | 27 | $418 to $996 | $724 |
| UnitedHealthcare | 29 | $511 to $983 | $703 |
| Aetna | 9 | $655 to $1,023 | $755 |
| Cigna | 3 | $836 to $922 | $880 |
Rates are negotiated allowed amounts and cash prices from hospital price-transparency files (October 2026), shown at each hospital’s lowest-priced typical billing code for this procedure. Facility fees only. The typical range is the middle 80% of hospitals, not a quote for your visit.
How much does a chemotherapy infusion cost with Medicare in South Dakota?
Medicare's national hospital outpatient payment for chemotherapy infusion is about $337 to $337 (typically near $337). After the $257 Part B deductible, you generally pay 20% of the Medicare-approved amount, about $67 on a $337 payment, with no out-of-pocket cap unless you have supplemental coverage or a Medicare Advantage plan.
Doctor, anesthesia and pathology fees are billed separately. Medicare rates are national CMS amounts, adjusted slightly by local wage levels.
How much does a chemotherapy infusion cost with insurance in South Dakota?
Across 34 South Dakota hospitals, the negotiated rates commercial insurers pay for chemotherapy infusion average $351 to $907 per hospital, with a median near $620. That is the amount your plan and you pay the hospital together; you owe your deductible, then coinsurance, up to your out-of-pocket maximum.
Each hospital’s figure is the average of the commercial insurers it lists. Medicare, Medicare Advantage and Medicaid rates are excluded.
How much does a chemotherapy infusion cost without insurance in South Dakota?
Cash (self-pay) prices for chemotherapy infusion at 37 South Dakota hospitals range from $585 to $1,014, with a median of $798. Ask for the cash or self-pay price and for any financial-assistance discount before you book; both can be lower than the posted price.
Cash prices are the hospital’s published discounted rate for patients paying without insurance.
How much does a chemotherapy infusion cost with Wellmark Blue Cross and Blue Shield of South Dakota?
Wellmark Blue Cross and Blue Shield of South Dakota negotiated rates for chemotherapy infusion at 27 South Dakota hospitals range from $418 to $996, with a median near $724. Your own cost depends on your plan’s deductible and coinsurance, and on whether the hospital is in your network.
Includes Blue Cross and Blue Shield and Anthem plans listed by each hospital.
How much does a chemotherapy infusion cost with UnitedHealthcare in South Dakota?
UnitedHealthcare negotiated rates for chemotherapy infusion at 29 South Dakota hospitals range from $511 to $983, with a median near $703. If a hospital is out of network for your UnitedHealthcare plan, you may owe more than the negotiated rate, so check the network first.
How much does a chemotherapy infusion cost with Aetna in South Dakota?
Aetna negotiated rates for chemotherapy infusion at 9 South Dakota hospitals range from $655 to $1,023, with a median near $755. If a hospital is out of network for your Aetna plan, you may owe more than the negotiated rate, so check the network first.
How much does a chemotherapy infusion cost with Cigna in South Dakota?
Cigna negotiated rates for chemotherapy infusion at 3 South Dakota hospitals range from $836 to $922, with a median near $880. If a hospital is out of network for your Cigna plan, you may owe more than the negotiated rate, so check the network first.
How where you go changes what you pay for chemotherapy infusion
The same chemotherapy infusion bundles different services depending on the setting - facility fee, surgeon fee, and anesthesia each arrive as separate bills. Estimated ranges below reflect the typical full bundled cost, including all expected charges.
- Facility fee $144–$1,408
- Professional fee $185–$492
Estimated from CMS fee schedules + commercial rate multipliers
- Facility fee $642–$705
- Professional fee $185–$492
Estimated from CMS fee schedules + commercial rate multipliers
Sanford Health and Monument Health are the dominant systems. The Sanford Health network extends across both Dakotas and into Minnesota and Iowa, giving it extraordinary commercial contracting leverage. South Dakota's rural geography - and the Sanford network's reach - means most residents have very limited facility alternatives.
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Why prices vary - and what it means for your coverage
A small number of hospitals (2) report prices above $1,212, including Avera St. Benedicts at $1,408, which drives most of the overall spread - excluding them, most facilities cluster in a much tighter band. Setting matters too: the median outpatient price is $810 versus $674 inpatient, so where a procedure happens often matters more than which hospital you pick.
None of the prices above are what you'll necessarily owe: your deductible, out-of-pocket maximum, and each provider's network status all still apply.
| Your situation | Estimated out-of-pocket |
|---|---|
| Deductible not yet met | ~$798 |
| Deductible met - 20% coinsurance | ~$160 |
| Out-of-network provider | $1,756+ |
Frequently asked questions: chemotherapy infusion costs in South Dakota
How much does a chemotherapy infusion cost in South Dakota?
The typical insurer-negotiated rate is $316, with most facilities between $272 and $450 (based on 36 hospitals reporting negotiated rates). Posted cash prices at the middle 80% of South Dakota hospitals run $585–$1,014; outlier facilities above and below that range are left out. What you pay depends on the facility, your insurance, and whether you have met your deductible.
Where is the cheapest place to get a chemotherapy infusion in South Dakota?
Based on declared prices, the lowest posted price in our South Dakota data is Avera Sacred Heart Hospital in Yankton at about $629. By metro, Sioux Falls has the lowest median ($827).
Why is a chemotherapy infusion so much cheaper at some South Dakota hospitals?
Typical prices vary about 1.7× (25th to 70th percentile of negotiated rates) because each hospital sets its own list price, cash discount, and insurer-negotiated rates. In South Dakota, the median cash (self-pay) price is $798 versus a median negotiated rate of $620 - about 1.3× higher. Asking for the cash price as well as your insurer's negotiated rate is often the single biggest lever on what you pay.
How much will I actually pay out of pocket for a chemotherapy infusion in South Dakota?
Your out-of-pocket cost depends on your deductible, coinsurance, out-of-pocket maximum, and whether the facility is in-network - not just the sticker price. If you have not met your deductible, you will typically pay the negotiated rate in full until you do. Use the CostKits cost forecaster to estimate your specific out-of-pocket amount before you go.
Before you book
- Allowed amount vs negotiated rate: what your EOB is really saying
- How to read your medical bill
- Deductible vs out-of-pocket max
- Already have a bill? Check it for errors
- How to read an EOB line by line
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CostKits compiles hospital price transparency data to help families make informed decisions. Track and manage your healthcare costs (free account).
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About the Author
John Caruso, FSA, MAAA
Healthcare actuary with 20+ years of experience in insurance pricing, medical billing systems, and healthcare cost analytics.
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