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Reviewed by John Caruso, FSA, MAAA • Data last updated

Chemotherapy Infusion Cost in Pennsylvania (2026): Average Prices & What You'll Pay

What does a chemotherapy infusion cost in Pennsylvania?

Where you have a chemotherapy infusion done in Pennsylvania swings the bill from $200 to $562 for identical care. The median cash price across 93 reporting hospitals is $360. The numbers are pulled directly from federally mandated hospital price transparency files. The sections below break this down by coverage and by insurer.

Once you have a bill or an appointment on the calendar, CostKits can help you keep it all organized.

Where chemotherapy infusion costs vary in Pennsylvania

Pins show hospitals with price-transparency data (colored by vs. state average) and nearby outpatient clinics and other facilities (colored by type). Click any pin for facility name and estimated cost range.

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26+ people checked prices near them this month.

What you pay for a chemotherapy infusion depends on where you go and what is billed separately. Most patients find out after.

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  • ✓ The drugs are not included: Chemotherapy drugs are billed on their own and are usually most of the bill.
  • ✓ Time: The first hour is priced here, and each additional hour is an add-on.
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Cheapest Chemotherapy Infusion Providers in Pennsylvania

Based on declared cash/self-pay prices from CMS hospital price transparency files.

# Facility City Price vs median ($360)
1 Abington Memorial Hospital Abington, PA $114 $246 below
2 OSS Orthopaedic Hospital York, PA $114 $246 below
3 Jefferson Health - Northeast Langhorne, PA $114 $246 below
4 Lansdale Hospital Corp Lansdale, PA $114 $246 below
5 Thomas Jefferson University Hospital, Inc. Philadelphia, PA $114 $246 below
6 Butler Healthcare Providers_ DBA Butler Memorial Hospital PA $124 $236 below
7 Clarion Hospital PA $124 $236 below
8 Mount Nittany Health State College, PA $124 $236 below

Prices are declared self-pay rates. Contact each facility for a formal quote before scheduling.

Before you book: three questions that change the price

  1. Is this the self-pay price, and does it include the doctor, anesthesia and any lab or pathology? Those are often billed separately.
  2. Can you give me the price in writing, with the billing codes it covers?
  3. What happens to the price if something extra is needed during the procedure?

Estimate your out-of-pocket cost →  ·  When the bills arrive, we check them for errors →

Quick take

  • Abington Memorial Hospital is the lowest-cost option at $114 - $246 below the median posted price ($360), just by choosing where you go.
  • Ask for the cash price if your deductible isn't met - the median cash price here is $360, and it's often lower than what insurance pays before your deductible is satisfied.
  • Doctor offices and independent clinics may charge differently from hospitals for the same service and may not appear in this hospital-only dataset. Ask your doctor whether another site is an option.
Chemotherapy infusion prices by coverage in Pennsylvania, October 2026
CoverageHospitals with a rateTypical rangeMedian
Medicare (national rate)—$337 to $337$337
With insurance (commercial, average)79$277 to $908$396
Without insurance (cash price)98$114 to $815$360
Highmark Blue Cross Blue Shield72$105 to $723$294
Aetna64$239 to $1,063$590
Cigna58$270 to $1,112$458
UnitedHealthcare51$190 to $1,345$334

Rates are negotiated allowed amounts and cash prices from hospital price-transparency files (October 2026), shown at each hospital’s lowest-priced typical billing code for this procedure. Facility fees only. The typical range is the middle 80% of hospitals, not a quote for your visit.

How much does a chemotherapy infusion cost with Medicare in Pennsylvania?

Medicare's national hospital outpatient payment for chemotherapy infusion is about $337 to $337 (typically near $337). After the $257 Part B deductible, you generally pay 20% of the Medicare-approved amount, about $67 on a $337 payment, with no out-of-pocket cap unless you have supplemental coverage or a Medicare Advantage plan.

Doctor, anesthesia and pathology fees are billed separately. Medicare rates are national CMS amounts, adjusted slightly by local wage levels.

How much does a chemotherapy infusion cost with insurance in Pennsylvania?

Across 79 Pennsylvania hospitals, the negotiated rates commercial insurers pay for chemotherapy infusion average $277 to $908 per hospital, with a median near $396. That is the amount your plan and you pay the hospital together; you owe your deductible, then coinsurance, up to your out-of-pocket maximum.

Each hospital’s figure is the average of the commercial insurers it lists. Medicare, Medicare Advantage and Medicaid rates are excluded.

How much does a chemotherapy infusion cost without insurance in Pennsylvania?

Cash (self-pay) prices for chemotherapy infusion at 98 Pennsylvania hospitals range from $114 to $815, with a median of $360. Ask for the cash or self-pay price and for any financial-assistance discount before you book; both can be lower than the posted price.

Cash prices are the hospital’s published discounted rate for patients paying without insurance.

How much does a chemotherapy infusion cost with Highmark Blue Cross Blue Shield in Pennsylvania?

Highmark Blue Cross Blue Shield negotiated rates for chemotherapy infusion at 72 Pennsylvania hospitals range from $105 to $723, with a median near $294. Your own cost depends on your plan’s deductible and coinsurance, and on whether the hospital is in your network.

Includes Blue Cross and Blue Shield and Anthem plans listed by each hospital.

How much does a chemotherapy infusion cost with Aetna in Pennsylvania?

Aetna negotiated rates for chemotherapy infusion at 64 Pennsylvania hospitals range from $239 to $1,063, with a median near $590. If a hospital is out of network for your Aetna plan, you may owe more than the negotiated rate, so check the network first.

How much does a chemotherapy infusion cost with Cigna in Pennsylvania?

Cigna negotiated rates for chemotherapy infusion at 58 Pennsylvania hospitals range from $270 to $1,112, with a median near $458. If a hospital is out of network for your Cigna plan, you may owe more than the negotiated rate, so check the network first.

How much does a chemotherapy infusion cost with UnitedHealthcare in Pennsylvania?

UnitedHealthcare negotiated rates for chemotherapy infusion at 51 Pennsylvania hospitals range from $190 to $1,345, with a median near $334. If a hospital is out of network for your UnitedHealthcare plan, you may owe more than the negotiated rate, so check the network first.

How where you go changes what you pay for chemotherapy infusion

The same chemotherapy infusion bundles different services depending on the setting - facility fee, surgeon fee, and anesthesia each arrive as separate bills. Estimated ranges below reflect the typical full bundled cost, including all expected charges.

Hospital Outpatient
$217–$4,124
  • Facility fee $32–$3,632
  • Professional fee $185–$492

Estimated from CMS fee schedules + commercial rate multipliers

Hospital Inpatient
$357–$1,989
  • Facility fee $172–$1,497
  • Professional fee $185–$492

Estimated from CMS fee schedules + commercial rate multipliers

Pennsylvania has a highly fragmented hospital market - Penn Medicine, Jefferson Health, Temple Health, and Tower Health compete in Philadelphia; UPMC and Highmark/Allegheny Health Network are engaged in one of the country's most litigated payer-provider disputes in Pittsburgh. The UPMC vs. Highmark conflict has directly affected patients' ability to use their insurance at in-network facilities. Rural Pennsylvania prices are substantially lower than the two major metro markets.

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Why prices vary - and what it means for your coverage

A small number of hospitals (8) report prices above $1,123, including Presbyterian Medical Center of the University of Pennsylvania Health System D/B/A Penn Presbyterian Medical Center at $2,548, which drives most of the overall spread - excluding them, most facilities cluster in a much tighter band. Setting matters too: the median outpatient price is $346 versus $531 inpatient (about 1.5× more), so where a procedure happens often matters more than which hospital you pick.

On top of the facility price, your actual bill depends on your deductible, your out-of-pocket maximum, and whether every provider involved - not just the facility - is in-network.

Your situation Estimated out-of-pocket
Deductible not yet met ~$360
Deductible met - 20% coinsurance ~$72
Out-of-network provider $792+

Frequently asked questions: chemotherapy infusion costs in Pennsylvania

How much does a chemotherapy infusion cost in Pennsylvania?

The typical insurer-negotiated rate is $109, with most facilities between $40 and $131 (based on 93 hospitals reporting negotiated rates). Posted cash prices at the middle 80% of Pennsylvania hospitals run $114–$815; outlier facilities above and below that range are left out. What you pay depends on the facility, your insurance, and whether you have met your deductible.

Where is the cheapest place to get a chemotherapy infusion in Pennsylvania?

Based on declared prices, the lowest posted price in our Pennsylvania data is Abington Memorial Hospital in Abington at about $114. By metro, Erie has the lowest median ($200).

Why is a chemotherapy infusion so much cheaper at some Pennsylvania hospitals?

Typical prices vary about 3.3× (25th to 70th percentile of negotiated rates) because each hospital sets its own list price, cash discount, and insurer-negotiated rates. In Pennsylvania, the median cash (self-pay) price is $360 versus a median negotiated rate of $396 - cash is the lower number at many hospitals. Asking for the cash price as well as your insurer's negotiated rate is often the single biggest lever on what you pay.

How much will I actually pay out of pocket for a chemotherapy infusion in Pennsylvania?

Your out-of-pocket cost depends on your deductible, coinsurance, out-of-pocket maximum, and whether the facility is in-network - not just the sticker price. If you have not met your deductible, you will typically pay the negotiated rate in full until you do. Use the CostKits cost forecaster to estimate your specific out-of-pocket amount before you go.

Before you book

Other procedures in Pennsylvania

Chemotherapy Infusion, elsewhere

CostKits compiles hospital price transparency data to help families make informed decisions. Track and manage your healthcare costs (free account).

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About the Author

John Caruso, FSA, MAAA

Healthcare actuary with 20+ years of experience in insurance pricing, medical billing systems, and healthcare cost analytics.

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Published October 29, 2026 · Updated October 29, 2026

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