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Chemotherapy Infusion Cost in North Carolina (2026): Average Prices & What You'll Pay

What does a chemotherapy infusion cost in North Carolina?

The same chemotherapy infusion in North Carolina might cost you $320 at one facility and $664 at another - the building you walk into drives the difference. The median cash price across 73 reporting hospitals is $393. These figures come straight from hospital price transparency files published under federal law. The sections below break this down by coverage and by insurer.

Three low-priced facilities in North Carolina, from hospital price files

  • DUKE UNIVERSITY HEALTH SYSTEM, INC. Doing Business As: DURHAM REGIONAL HOSPITAL · Durham, NC $248
  • DUKE UNIVERSITY HEALTH SYSTEM, INC. Doing Business As: DUKE UNIVERSITY HOSPITAL · Durham, NC $248
  • Forsyth Memorial Hospital, Inc. · Winston-Salem, NC $249

All 73 facilities are listed below, free.

Where chemotherapy infusion costs vary in North Carolina

Pins show hospitals with price-transparency data (colored by vs. state average) and nearby outpatient clinics and other facilities (colored by type). Click any pin for facility name and estimated cost range.

Hospital (below avg) Hospital (above avg) Click a pin for details.

26+ people checked prices near them this month.

What you pay for a chemotherapy infusion depends on where you go and what is billed separately. Most patients find out after.

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  • ✓ The drugs are not included: Chemotherapy drugs are billed on their own and are usually most of the bill.
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Cheapest Chemotherapy Infusion Providers in North Carolina

Based on declared cash/self-pay prices from CMS hospital price transparency files.

# Facility City Price vs median ($393)
1 DUKE UNIVERSITY HEALTH SYSTEM, INC. Doing Business As: DURHAM REGIONAL HOSPITAL Durham, NC $248 $145 below
2 DUKE UNIVERSITY HEALTH SYSTEM, INC. Doing Business As: DUKE UNIVERSITY HOSPITAL Durham, NC $248 $145 below
3 Forsyth Memorial Hospital, Inc. Winston-Salem, NC $249 $144 below
4 FIRSTHEALTH OF THE CAROLINAS, INC Troy, NC $252 $141 below
5 East Carolina Health-Chowan, Inc. Edenton, NC $264 $129 below
6 Duplin General Hospital, Inc. Kenansville, NC $272 $121 below
7 Rex Hospital, Inc. Raleigh, NC $273 $120 below
8 Lenoir Memorial Hospital Kinston, NC $273 $120 below

Prices are declared self-pay rates. Contact each facility for a formal quote before scheduling.

Before you book: three questions that change the price

  1. Is this the self-pay price, and does it include the doctor, anesthesia and any lab or pathology? Those are often billed separately.
  2. Can you give me the price in writing, with the billing codes it covers?
  3. What happens to the price if something extra is needed during the procedure?

Estimate your out-of-pocket cost →  ·  When the bills arrive, we check them for errors →

Quick take

  • DUKE UNIVERSITY HEALTH SYSTEM, INC. Doing Business As: DURHAM REGIONAL HOSPITAL is the lowest-cost option at $248 - $145 below the median posted price ($393), just by choosing where you go.
  • Ask for the cash price if your deductible isn't met - the median cash price here is $393, and it's often lower than what insurance pays before your deductible is satisfied.
  • Doctor offices and independent clinics may charge differently from hospitals for the same service and may not appear in this hospital-only dataset. Ask your doctor whether another site is an option.
Chemotherapy infusion prices by coverage in North Carolina, October 2026
CoverageHospitals with a rateTypical rangeMedian
Medicare (national rate)—$337 to $337$337
With insurance (commercial, average)66$301 to $748$487
Without insurance (cash price)88$248 to $829$393
Blue Cross and Blue Shield of North Carolina49$208 to $621$389
Aetna53$313 to $805$503
Cigna51$252 to $770$524
UnitedHealthcare34$282 to $766$352

Rates are negotiated allowed amounts and cash prices from hospital price-transparency files (October 2026), shown at each hospital’s lowest-priced typical billing code for this procedure. Facility fees only. The typical range is the middle 80% of hospitals, not a quote for your visit.

How much does a chemotherapy infusion cost with Medicare in North Carolina?

Medicare's national hospital outpatient payment for chemotherapy infusion is about $337 to $337 (typically near $337). After the $257 Part B deductible, you generally pay 20% of the Medicare-approved amount, about $67 on a $337 payment, with no out-of-pocket cap unless you have supplemental coverage or a Medicare Advantage plan.

Doctor, anesthesia and pathology fees are billed separately. Medicare rates are national CMS amounts, adjusted slightly by local wage levels.

How much does a chemotherapy infusion cost with insurance in North Carolina?

Across 66 North Carolina hospitals, the negotiated rates commercial insurers pay for chemotherapy infusion average $301 to $748 per hospital, with a median near $487. That is the amount your plan and you pay the hospital together; you owe your deductible, then coinsurance, up to your out-of-pocket maximum.

Each hospital’s figure is the average of the commercial insurers it lists. Medicare, Medicare Advantage and Medicaid rates are excluded.

How much does a chemotherapy infusion cost without insurance in North Carolina?

Cash (self-pay) prices for chemotherapy infusion at 88 North Carolina hospitals range from $248 to $829, with a median of $393. Ask for the cash or self-pay price and for any financial-assistance discount before you book; both can be lower than the posted price.

Cash prices are the hospital’s published discounted rate for patients paying without insurance.

How much does a chemotherapy infusion cost with Blue Cross and Blue Shield of North Carolina?

Blue Cross and Blue Shield of North Carolina negotiated rates for chemotherapy infusion at 49 North Carolina hospitals range from $208 to $621, with a median near $389. Your own cost depends on your plan’s deductible and coinsurance, and on whether the hospital is in your network.

Includes Blue Cross and Blue Shield and Anthem plans listed by each hospital.

How much does a chemotherapy infusion cost with Aetna in North Carolina?

Aetna negotiated rates for chemotherapy infusion at 53 North Carolina hospitals range from $313 to $805, with a median near $503. If a hospital is out of network for your Aetna plan, you may owe more than the negotiated rate, so check the network first.

How much does a chemotherapy infusion cost with Cigna in North Carolina?

Cigna negotiated rates for chemotherapy infusion at 51 North Carolina hospitals range from $252 to $770, with a median near $524. If a hospital is out of network for your Cigna plan, you may owe more than the negotiated rate, so check the network first.

How much does a chemotherapy infusion cost with UnitedHealthcare in North Carolina?

UnitedHealthcare negotiated rates for chemotherapy infusion at 34 North Carolina hospitals range from $282 to $766, with a median near $352. If a hospital is out of network for your UnitedHealthcare plan, you may owe more than the negotiated rate, so check the network first.

How where you go changes what you pay for chemotherapy infusion

The same chemotherapy infusion bundles different services depending on the setting - facility fee, surgeon fee, and anesthesia each arrive as separate bills. Estimated ranges below reflect the typical full bundled cost, including all expected charges.

Hospital Outpatient
$364–$2,565
  • Facility fee $179–$2,073
  • Professional fee $185–$492

Estimated from CMS fee schedules + commercial rate multipliers

Hospital Inpatient
$369–$2,565
  • Facility fee $184–$2,073
  • Professional fee $185–$492

Estimated from CMS fee schedules + commercial rate multipliers

Atrium Health (formerly Carolinas HealthCare) and Wake Forest Baptist Health have merged into one of the largest nonprofit health systems in the Southeast. Duke Health and UNC Health anchor the Research Triangle academic tier, creating a market where major academic centers hold outsized pricing leverage. North Carolina has been an active target for FTC scrutiny of hospital consolidation.

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Why prices vary - and what it means for your coverage

A small number of hospitals (2) report prices above $1,516, including Pitt County Memorial Hospital, Inc. at $2,073, which drives most of the overall spread - excluding them, most facilities cluster in a much tighter band. Setting matters too: the median outpatient price is $382 versus $275 inpatient, so where a procedure happens often matters more than which hospital you pick.

On top of the facility price, your actual bill depends on your deductible, your out-of-pocket maximum, and whether every provider involved - not just the facility - is in-network.

Your situation Estimated out-of-pocket
Deductible not yet met ~$393
Deductible met - 20% coinsurance ~$79
Out-of-network provider $865+

Frequently asked questions: chemotherapy infusion costs in North Carolina

How much does a chemotherapy infusion cost in North Carolina?

The typical insurer-negotiated rate is $194, with most facilities between $130 and $287 (based on 73 hospitals reporting negotiated rates). Posted cash prices at the middle 80% of North Carolina hospitals run $248–$829; outlier facilities above and below that range are left out. What you pay depends on the facility, your insurance, and whether you have met your deductible.

Where is the cheapest place to get a chemotherapy infusion in North Carolina?

Based on declared prices, the lowest posted price in our North Carolina data is DUKE UNIVERSITY HEALTH SYSTEM, INC. Doing Business As: DURHAM REGIONAL HOSPITAL in Durham at about $248. By metro, Durham has the lowest median ($248).

Why is a chemotherapy infusion so much cheaper at some North Carolina hospitals?

Typical prices vary about 2.2× (25th to 70th percentile of negotiated rates) because each hospital sets its own list price, cash discount, and insurer-negotiated rates. In North Carolina, the median cash (self-pay) price is $393 versus a median negotiated rate of $487 - cash is the lower number at many hospitals. Asking for the cash price as well as your insurer's negotiated rate is often the single biggest lever on what you pay.

How much will I actually pay out of pocket for a chemotherapy infusion in North Carolina?

Your out-of-pocket cost depends on your deductible, coinsurance, out-of-pocket maximum, and whether the facility is in-network - not just the sticker price. If you have not met your deductible, you will typically pay the negotiated rate in full until you do. Use the CostKits cost forecaster to estimate your specific out-of-pocket amount before you go.

Before you book

Other procedures in North Carolina

Chemotherapy Infusion, elsewhere


CostKits compiles hospital price transparency data to help families make informed decisions. Track and manage your healthcare costs (free account).

Other Procedure Costs in North Carolina

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Bone, joint and pain

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Ear, nose and throat

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Eye care

Emergency care

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About the Author

John Caruso, FSA, MAAA

Healthcare actuary with 20+ years of experience in insurance pricing, medical billing systems, and healthcare cost analytics.

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Published October 29, 2026 · Updated October 29, 2026

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