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Reviewed by John Caruso, FSA, MAAA • Data last updated

Chemotherapy Infusion Cost in Massachusetts (2026): Average Prices & What You'll Pay

What does a chemotherapy infusion cost in Massachusetts?

Where you have a chemotherapy infusion done in Massachusetts swings the bill from $464 to $1,029 for identical care. The median cash price across 51 reporting hospitals is $648. The numbers are pulled directly from federally mandated hospital price transparency files. The sections below break this down by coverage and by insurer.

Once you have a bill or an appointment on the calendar, CostKits can help you keep it all organized.

Where chemotherapy infusion costs vary in Massachusetts

Pins show hospitals with price-transparency data (colored by vs. state average) and nearby outpatient clinics and other facilities (colored by type). Click any pin for facility name and estimated cost range.

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26+ people checked prices near them this month.

What you pay for a chemotherapy infusion depends on where you go and what is billed separately. Most patients find out after.

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  • ✓ The drugs are not included: Chemotherapy drugs are billed on their own and are usually most of the bill.
  • ✓ Time: The first hour is priced here, and each additional hour is an add-on.
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Cheapest Chemotherapy Infusion Providers in Massachusetts

Based on declared cash/self-pay prices from CMS hospital price transparency files.

# Facility City Price vs median ($648)
1 The Mercy Hospital Inc Springfield, MA $393 $255 below
2 Saint Anne's Hospital, Lifespan of Massachusetts - Fall River Inc Fall River, MA $395 $253 below
3 Morton Hospital and Medical Center, Inc., Lifespan of Massachusetts - Taunton Inc Taunton, MA $395 $253 below
4 Mount Auburn Hospital Cambridge, MA $395 $253 below
5 Boston Medical Center South MA $396 $252 below
6 Southcoast Hospitals Group, Inc. MA $414 $234 below
7 Beth Israel Deaconess Hospital-Milton Inc Milton, MA $429 $219 below
8 Boston Medical Center Brighton MA $452 $196 below

Prices are declared self-pay rates. Contact each facility for a formal quote before scheduling.

Before you book: three questions that change the price

  1. Is this the self-pay price, and does it include the doctor, anesthesia and any lab or pathology? Those are often billed separately.
  2. Can you give me the price in writing, with the billing codes it covers?
  3. What happens to the price if something extra is needed during the procedure?

Estimate your out-of-pocket cost →  ·  When the bills arrive, we check them for errors →

Quick take

  • The Mercy Hospital Inc is the lowest-cost option at $393 - $255 below the median posted price ($648), just by choosing where you go.
  • Ask for the cash price if your deductible isn't met - the median cash price here is $648, and it's often lower than what insurance pays before your deductible is satisfied.
  • Doctor offices and independent clinics may charge differently from hospitals for the same service and may not appear in this hospital-only dataset. Ask your doctor whether another site is an option.
Chemotherapy infusion prices by coverage in Massachusetts, October 2026
CoverageHospitals with a rateTypical rangeMedian
Medicare (national rate)—$337 to $337$337
With insurance (commercial, average)31$393 to $1,079$640
Without insurance (cash price)62$321 to $2,971$648
Blue Cross Blue Shield of Massachusetts30$389 to $745$546
UnitedHealthcare18$232 to $1,483$436
Aetna14$258 to $1,494$833
Cigna14$377 to $1,515$733

Rates are negotiated allowed amounts and cash prices from hospital price-transparency files (October 2026), shown at each hospital’s lowest-priced typical billing code for this procedure. Facility fees only. The typical range is the middle 80% of hospitals, not a quote for your visit.

How much does a chemotherapy infusion cost with Medicare in Massachusetts?

Medicare's national hospital outpatient payment for chemotherapy infusion is about $337 to $337 (typically near $337). After the $257 Part B deductible, you generally pay 20% of the Medicare-approved amount, about $67 on a $337 payment, with no out-of-pocket cap unless you have supplemental coverage or a Medicare Advantage plan.

Doctor, anesthesia and pathology fees are billed separately. Medicare rates are national CMS amounts, adjusted slightly by local wage levels.

How much does a chemotherapy infusion cost with insurance in Massachusetts?

Across 31 Massachusetts hospitals, the negotiated rates commercial insurers pay for chemotherapy infusion average $393 to $1,079 per hospital, with a median near $640. That is the amount your plan and you pay the hospital together; you owe your deductible, then coinsurance, up to your out-of-pocket maximum.

Each hospital’s figure is the average of the commercial insurers it lists. Medicare, Medicare Advantage and Medicaid rates are excluded.

How much does a chemotherapy infusion cost without insurance in Massachusetts?

Cash (self-pay) prices for chemotherapy infusion at 62 Massachusetts hospitals range from $321 to $2,971, with a median of $648. Ask for the cash or self-pay price and for any financial-assistance discount before you book; both can be lower than the posted price.

Cash prices are the hospital’s published discounted rate for patients paying without insurance.

How much does a chemotherapy infusion cost with Blue Cross Blue Shield of Massachusetts?

Blue Cross Blue Shield of Massachusetts negotiated rates for chemotherapy infusion at 30 Massachusetts hospitals range from $389 to $745, with a median near $546. Your own cost depends on your plan’s deductible and coinsurance, and on whether the hospital is in your network.

Includes Blue Cross and Blue Shield and Anthem plans listed by each hospital.

How much does a chemotherapy infusion cost with UnitedHealthcare in Massachusetts?

UnitedHealthcare negotiated rates for chemotherapy infusion at 18 Massachusetts hospitals range from $232 to $1,483, with a median near $436. If a hospital is out of network for your UnitedHealthcare plan, you may owe more than the negotiated rate, so check the network first.

How much does a chemotherapy infusion cost with Aetna in Massachusetts?

Aetna negotiated rates for chemotherapy infusion at 14 Massachusetts hospitals range from $258 to $1,494, with a median near $833. If a hospital is out of network for your Aetna plan, you may owe more than the negotiated rate, so check the network first.

How much does a chemotherapy infusion cost with Cigna in Massachusetts?

Cigna negotiated rates for chemotherapy infusion at 14 Massachusetts hospitals range from $377 to $1,515, with a median near $733. If a hospital is out of network for your Cigna plan, you may owe more than the negotiated rate, so check the network first.

How where you go changes what you pay for chemotherapy infusion

The same chemotherapy infusion bundles different services depending on the setting - facility fee, surgeon fee, and anesthesia each arrive as separate bills. Estimated ranges below reflect the typical full bundled cost, including all expected charges.

Hospital Outpatient
$286–$3,463
  • Facility fee $101–$2,971
  • Professional fee $185–$492

Estimated from CMS fee schedules + commercial rate multipliers

Hospital Inpatient
$330–$3,463
  • Facility fee $145–$2,971
  • Professional fee $185–$492

Estimated from CMS fee schedules + commercial rate multipliers

Massachusetts has the highest commercial hospital reimbursement rates in the country, driven by extreme labor costs, the dominance of Mass General Brigham (Partners HealthCare), and a regulatory environment that has struggled to contain negotiated rate growth. The state has enacted multiple price transparency and rate growth laws aimed at curbing this pattern. Self-pay cash discounts in Massachusetts tend to be proportionally larger than in other high-cost states.

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Why prices vary - and what it means for your coverage

A small number of hospitals (9) report prices above $2,522, including Boston Children's Hospital at $2,971, which drives most of the overall spread - excluding them, most facilities cluster in a much tighter band. Setting matters too: the median outpatient price is $636 versus $1,061 inpatient (about 1.7× more), so where a procedure happens often matters more than which hospital you pick.

None of the prices above are what you'll necessarily owe: your deductible, out-of-pocket maximum, and each provider's network status all still apply.

Your situation Estimated out-of-pocket
Deductible not yet met ~$648
Deductible met - 20% coinsurance ~$130
Out-of-network provider $1,426+

Frequently asked questions: chemotherapy infusion costs in Massachusetts

How much does a chemotherapy infusion cost in Massachusetts?

The typical insurer-negotiated rate is $312, with most facilities between $177 and $395 (based on 51 hospitals reporting negotiated rates). Posted cash prices at the middle 80% of Massachusetts hospitals run $321–$2,971; outlier facilities above and below that range are left out. What you pay depends on the facility, your insurance, and whether you have met your deductible.

Where is the cheapest place to get a chemotherapy infusion in Massachusetts?

Based on declared prices, the lowest posted price in our Massachusetts data is The Mercy Hospital Inc in Springfield at about $393. By metro, Cambridge has the lowest median ($460).

Why is a chemotherapy infusion so much cheaper at some Massachusetts hospitals?

Typical prices vary about 2.2× (25th to 70th percentile of negotiated rates) because each hospital sets its own list price, cash discount, and insurer-negotiated rates. In Massachusetts, the median cash (self-pay) price is $648 versus a median negotiated rate of $640 - about 1× higher. Asking for the cash price as well as your insurer's negotiated rate is often the single biggest lever on what you pay.

How much will I actually pay out of pocket for a chemotherapy infusion in Massachusetts?

Your out-of-pocket cost depends on your deductible, coinsurance, out-of-pocket maximum, and whether the facility is in-network - not just the sticker price. If you have not met your deductible, you will typically pay the negotiated rate in full until you do. Use the CostKits cost forecaster to estimate your specific out-of-pocket amount before you go.

Before you book

Other procedures in Massachusetts

Chemotherapy Infusion, elsewhere

CostKits compiles hospital price transparency data to help families make informed decisions. Track and manage your healthcare costs (free account).

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About the Author

John Caruso, FSA, MAAA

Healthcare actuary with 20+ years of experience in insurance pricing, medical billing systems, and healthcare cost analytics.

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Published October 29, 2026 · Updated October 29, 2026

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